Bosentan-d4 is the deuterium-labeled (d4) analogue of bosentan, a competitive, dual antagonist of endothelin-1 at ETA and ETB receptors. It is used primarily as an analytical internal standard and tracer for LC-MS/MS, pharmacokinetic, and ADME studies, providing matched chromatographic behavior with a distinct mass.
- Deuterium-labeled (d4) analogue for accurate mass spectrometry quantitation.
- Used as an internal standard in pharmacokinetic and ADME studies.
- Chemical formula C27H29N5O6S and molecular weight 555.6 g/mol.
- Purity 98% suitable for analytical applications.
- Acts as a dual ETA/ETB endothelin-1 receptor antagonist (analogue of bosentan).